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It is also used to treat pain caused by complications of diabetes or pain caused by fibromyalgia. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.</p> <h2>What should I tell my health care providers before I take this medicine?</h2> <p>They need to know if you have any of these conditions:</p> <ul> <li>bipolar disorder or a family history of bipolar disorder </li> <li>kidney or liver disease </li> <li>narrow- angle glaucoma </li> <li>suicidal thoughts or a previous suicide attempt </li> <li>taken medicines called MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate within 14 days </li> <li>an unusual reaction to duloxetine, other medicines, foods, dyes, or preservatives </li> <li>pregnant or trying to get pregnant </li> <li>breast-feeding</li> </ul> <h2>How should I use this medicine?</h2> <p>Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. 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If it is almost time for your next dose, take only that dose. Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <p>Do not take this medicine with any of the following:</p> <ul> <li>certain diet drugs like dexfenfluramine, fenfluramine, phentermine, sibutramine </li> <li>MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate </li> <li>nefazodone </li> <li>procarbazine </li> <li>SSRIs like citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline </li> <li>St. John's Wort </li> <li>thioridazine </li> <li>tryptophan </li> <li>venlafaxine </li> </ul> <p>This medicine may also interact with the following:</p> <ul> <li>certain antibiotics like ciprofloxacin and enoxacin </li> <li>cimetidine </li> <li>medicines for heart rhythm or blood pressure </li> <li>other medicines for mental depression, mania, psychosis, or anxiety</li> </ul> <p>This list may not describe all possible interactions. 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Do not cut, crush or chew this medicine. You can take this medicine with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. If you have been taking this medicine regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose, or your symptoms may get worse. Ask your doctor or health care professional for advice.</p> <p>A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.</p> <p>Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.</p> <p>Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.</p> <p>Note: This medicine is only for you. Do not share this medicine with others.</p> <h2>What if I miss a dose?</h2> <p>If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <p>Do not take this medicine with any of the following:</p> <ul> <li>certain diet drugs like dexfenfluramine, fenfluramine, phentermine, sibutramine </li> <li>MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate </li> <li>nefazodone </li> <li>procarbazine </li> <li>SSRIs like citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline </li> <li>St. John's Wort </li> <li>thioridazine </li> <li>tryptophan </li> <li>venlafaxine </li> </ul> <p>This medicine may also interact with the following:</p> <ul> <li>certain antibiotics like ciprofloxacin and enoxacin </li> <li>cimetidine </li> <li>medicines for heart rhythm or blood pressure </li> <li>other medicines for mental depression, mania, psychosis, or anxiety</li> </ul> <p>This list may not describe all possible interactions. 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